Cholinesterase substrates

Name
Cholinesterase substrates
Accession Number
DBCAT004572
Description

Not Available

Drugs
Drug Drug Description
Cocaine An ester local anesthetic used during diagnostic procedures and surgeries in or through the nasal cavities.
Succinylcholine A depolarizing skeletal muscle relaxant used adjunctly to anesthesia and for skeletal muscle relaxation during intubation, mechanical ventilation, and surgical procedures.
Trimethaphan For the controlled reduction of blood pressure during surgery and in the treatment of hypertensive emergencies.
Procaine A local anesthetic used for anesthesia, peripheral nerve block, and spinal nerve block.
Tubocurarine Tubocurarine is a non-depolarizing neuromuscular blocking agent and the first identified curare alkaloid. Curare is one of the names used to describe plant-derived poisons used by indigenous South Americans to...
Bambuterol A long acting beta2-adrenoceptor agonist for the management of lung diseases associated with bronchospasm.
Dipivefrin A prodrug of epinephrine used in ophthalmic solutions to reduce intraocular pressure in chronic open-angle glaucoma.
Chloroprocaine A local anesthetic agent indicated for intrathecal injection in adults for the production of subarachnoid block, spinal anesthesia, or ocular surface anesthesia.
Clevidipine A dihydropyridine L-type calcium channel blocker used to lower blood pressure when oral antihypertensive therapy is not feasible or not desirable.
Cyclopentolate An anticholinergic used to cause mydriasis and cycloplegia for diagnostic testing.
Doxacurium A nondepolarizing neuromuscular blocking agent used as an adjunct to general anesthesia to facilitate tracheal intubation, and to provide skeletal muscle relaxation during surgical procedures.
Ephedrine An alpha and beta-adrenergic agonist indicated to treat hypotension under anesthesia, allergic conditions, bronchial asthma, and nasal congestion.
Oxybuprocaine 一个局部麻醉用于眼科。
Sar9, Met (O2)11-Substance P Investigated for use/treatment in acute respiratory distress syndrome (ARDS) and viral infection.
Mirabegron A beta-3 adrenergic agonist used to treat overactive bladder and neurogenic detrusor overactivity.
Aclidinium An inhaled long-acting anticholinergic used as a maintenance bronchodilator in patients with chronic obstructive pulmonary disease (COPD).
Irinotecan An antineoplastic enzyme inhibitor used to treat metastatic carcinoma of the colon or rectum.
Moxisylyte By the WHO, moxisylyte is indicated for the symptomatic management of sequelae of cerebral infarction or hemorrhage. The cerebral infarction is characterized by the blockage of the artery either by...
Propacetamol Propacetamol is a paracetamol prodrug of intravenous administration used to control fever and pain of perioperative period in multimodal analgesia therapy.
Butamben Anesthesia of mucus membranes other than the eyes.
Butyrylthiocholine A sulfur-containing analog of butyrylcholine which is hydrolyzed by butyrylcholinesterase to butyrate and thiocholine. It is used as a reagent in the determination of butyrylcholinesterase activity. [PubChem]
Benzonatate A non-narcotic oral antitussive drug used to suppress coughing.
Pyridostigmine 胆碱酯酶抑制剂用于tr症状eatment of myasthenia gravis and congenital myasthenic syndromes and to reverse neuromuscular blockade by nondepolarizing muscle relaxants.
Mivacurium A short-acting non-depolarizing neuromuscular blocking agent used to induce anesthesia during intubation and promote skeletal muscle relaxation during surgery or mechanical ventilation.
Acetylcholine A parasympathomimetic neurotransmitter used to induce miosis of the iris in seconds after delivery of the lens in cataract surgery, in penetrating keratoplasty, iridectomy and other anterior segment surgery where rapid miosis may be required.
Drugs & Drug Targets
Drug Target Type
Cocaine Sodium-dependent noradrenaline transporter target
Cocaine Sodium channel protein target
Cocaine Sodium-dependent serotonin transporter target
Cocaine Sodium-dependent dopamine transporter target
Cocaine Cytochrome P450 3A4 enzyme
Cocaine Muscarinic acetylcholine receptor M1 target
Cocaine Muscarinic acetylcholine receptor M2 target
Cocaine Cytochrome P450 2D6 enzyme
Cocaine 溶质carrier family 22 member 2 transporter
Cocaine Cytochrome P450 2C8 enzyme
Cocaine Sigma non-opioid intracellular receptor 1 target
Cocaine Liver carboxylesterase 1 target
Cocaine Cholinesterase enzyme
Cocaine Sodium-dependent dopamine transporter transporter
Cocaine alpha1-acid glycoprotein carrier
Cocaine Liver carboxylesterase 1 enzyme
Succinylcholine Cholinesterase enzyme
Succinylcholine Muscarinic acetylcholine receptor M2 target
Succinylcholine Muscarinic acetylcholine receptor M3 target
Succinylcholine Neuronal Acetylcholine (nACh) Receptor Subunits target
Trimethaphan Neuronal acetylcholine receptor subunit alpha-10 target
Trimethaphan Cholinesterase enzyme
Procaine Sodium channel protein type 10 subunit alpha target
Procaine Glutamate receptor ionotropic, NMDA 3A target
Procaine 5-hydroxytryptamine receptor 3A target
Procaine Sodium-dependent dopamine transporter target
Procaine Neuronal acetylcholine receptor subunit alpha-2 target
Procaine Cholinesterase enzyme
Procaine DNA (cytosine-5)-methyltransferase 1 target
Procaine Calcium-activated potassium channel target
Procaine Cytosolic phospholipase A2 target
Procaine 60 kDa lysophospholipase target
Procaine Monoamine oxidase target
Procaine Sodium-dependent dopamine transporter transporter
Procaine Sodium-dependent noradrenaline transporter transporter
Procaine Sodium-dependent serotonin transporter transporter
Procaine DNA (cytosine-5)-methyltransferase 3A target
Tubocurarine Neuronal acetylcholine receptor subunit alpha-2 target
Tubocurarine Acetylcholinesterase target
Tubocurarine 5-hydroxytryptamine receptor 3A target
Tubocurarine 溶质carrier family 22 member 1 transporter
Tubocurarine 溶质carrier family 22 member 2 transporter
Tubocurarine Neuronal acetylcholine receptor subunit alpha-7 target
Tubocurarine Cholinesterase enzyme
Bambuterol Beta-2 adrenergic receptor target
Bambuterol Cholinesterase enzyme
Bambuterol Cholinesterase target
Dipivefrin Alpha-2A adrenergic receptor target
Dipivefrin Cholinesterase target
Dipivefrin Beta-2 adrenergic receptor target
Dipivefrin Alpha-1A adrenergic receptor target
Dipivefrin Acetylcholinesterase target
Chloroprocaine Sodium-dependent dopamine transporter target
Chloroprocaine Cholinesterase enzyme
Chloroprocaine Voltage-gated sodium channel alpha subunit target
Clevidipine Voltage-dependent L-type calcium channel subunit alpha-1F target
Clevidipine Voltage-dependent L-type calcium channel subunit alpha-1S target
Clevidipine Voltage-dependent L-type calcium channel subunit alpha-1D target
Clevidipine Voltage-dependent L-type calcium channel subunit alpha-1C target
Clevidipine Cytochrome P450 2C9 enzyme
Clevidipine Cytochrome P450 2D6 enzyme
Clevidipine Cytochrome P450 2E1 enzyme
Clevidipine Cytochrome P450 2C19 enzyme
Clevidipine Cytochrome P450 3A4 enzyme
Clevidipine Cholinesterase enzyme
Cyclopentolate Muscarinic acetylcholine receptor M1 target
Cyclopentolate Cholinesterase enzyme
Doxacurium Neuronal acetylcholine receptor subunit alpha-2 target
Doxacurium Muscarinic acetylcholine receptor M2 target
Doxacurium Cholinesterase enzyme
Ephedrine Alpha-1A adrenergic receptor target
Ephedrine Sodium-dependent noradrenaline transporter target
Ephedrine Cholinesterase enzyme
Ephedrine Serum albumin carrier
Ephedrine Beta-1 adrenergic receptor target
Ephedrine Beta-2 adrenergic receptor target
Ephedrine Synaptic vesicular amine transporter transporter
Ephedrine Acetylcholinesterase enzyme
Oxybuprocaine Sodium channel protein type 10 subunit alpha target
Oxybuprocaine Cholinesterase enzyme
Sar9, Met (O2)11-Substance P Cytochrome P450 19A1 enzyme
Sar9, Met (O2)11-Substance P Cholinesterase enzyme
Sar9, Met (O2)11-Substance P Prostaglandin G/H synthase 2 enzyme
Mirabegron Cytochrome P450 3A4 enzyme
Mirabegron Cytochrome P450 2D6 enzyme
Mirabegron P-glycoprotein 1 transporter
Mirabegron 溶质carrier organic anion transporter family member 1A2 transporter
Mirabegron Serum albumin carrier
Mirabegron Alpha-1-acid glycoprotein 1 carrier
Mirabegron Cholinesterase enzyme
Mirabegron Beta-3 adrenergic receptor target
Mirabegron UDP-glucuronosyltransferase 2B7 enzyme
Mirabegron UDP-glucuronosyltransferase 1-3 enzyme
Mirabegron UDP-glucuronosyltransferase 1-8 enzyme
Mirabegron 溶质carrier family 22 member 1 transporter
Mirabegron 溶质carrier family 22 member 2 transporter
Mirabegron 溶质carrier family 22 member 3 transporter
Mirabegron Beta-1 adrenergic receptor target
Aclidinium Muscarinic acetylcholine receptor M1 target
Aclidinium Muscarinic acetylcholine receptor M2 target
Aclidinium Muscarinic acetylcholine receptor M3 target
Aclidinium Muscarinic acetylcholine receptor M4 target
Aclidinium Muscarinic acetylcholine receptor M5 target
Aclidinium Cholinesterase enzyme
Irinotecan DNA topoisomerase I, mitochondrial target
Irinotecan DNA topoisomerase 1 target
Irinotecan Cytochrome P450 3A4 enzyme
Irinotecan Cytochrome P450 3A5 enzyme
Irinotecan UDP-glucuronosyltransferase 1-1 enzyme
Irinotecan UDP-glucuronosyltransferase 1-9 enzyme
Irinotecan Liver carboxylesterase 1 enzyme
Irinotecan Cytochrome P450 3A7 enzyme
Irinotecan Cytochrome P450 2B6 enzyme
Irinotecan 溶质carrier family 22 member 3 transporter
Irinotecan 溶质carrier organic anion transporter family member 1B1 transporter
Irinotecan Multidrug resistance-associated protein 1 transporter
Irinotecan ATP-binding cassette sub-family G member 2 transporter
Irinotecan Serum albumin carrier
Irinotecan Cocaine esterase enzyme
Irinotecan Cholinesterase enzyme
Irinotecan P-glycoprotein 1 transporter
Irinotecan Canalicular multispecific organic anion transporter 1 transporter
Moxisylyte Cholinesterase enzyme
Moxisylyte Cytochrome P450 3A Subfamily enzyme
Moxisylyte Alpha adrenergic receptor target
Propacetamol Cholinesterase enzyme
Propacetamol Prostaglandin G/H synthase 1 target
Propacetamol Prostaglandin G/H synthase 2 target
Propacetamol Transient receptor potential cation channel subfamily V member 1 target
Propacetamol Cannabinoid receptor 1 target
Propacetamol Cytochrome P450 2E1 enzyme
Propacetamol Cytochrome P450 1A2 enzyme
Propacetamol Cytochrome P450 2D6 enzyme
Propacetamol UDP-glucuronosyltransferase 1-1 enzyme
Propacetamol UDP-glucuronosyltransferase 1-6 enzyme
Propacetamol UDP-glucuronosyltransferase 1-9 enzyme
Propacetamol UDP-glucuronosyltransferase 2B15 enzyme
Propacetamol UDP-glucuronosyltransferase 1-10 enzyme
Propacetamol Sulfotransferase 1A1 enzyme
Propacetamol Sulfotransferase 1A3/1A4 enzyme
Propacetamol Estrogen sulfotransferase enzyme
Propacetamol Bile salt sulfotransferase enzyme
Propacetamol Arylamine N-acetyltransferase 2 enzyme
Propacetamol Cytochrome P450 2C9 enzyme
Propacetamol Cytochrome P450 3A4 enzyme
Butamben Voltage-dependent calcium channel target
Butamben Cholinesterase enzyme
Butamben Alpha-1-acid glycoprotein 1 carrier
Butamben Serum albumin carrier
Butamben ATP-sensitive potassium channel target
Butamben Transient receptor potential cation channel subfamily A member 1 target
Butamben Transient receptor potential cation channel subfamily V member 4 target
Butyrylthiocholine Cholinesterase target
Butyrylthiocholine Cholinesterase enzyme
Benzonatate Sodium channel protein type 5 subunit alpha target
Benzonatate Cholinesterase enzyme
Pyridostigmine Acetylcholinesterase target
Pyridostigmine Cholinesterase target
Pyridostigmine Acetylcholinesterase enzyme
Pyridostigmine Cholinesterase enzyme
Pyridostigmine Cytochrome P450 3A4 enzyme
Mivacurium Neuronal acetylcholine receptor subunit alpha-2 target
Mivacurium Muscarinic acetylcholine receptor M2 target
Mivacurium Muscarinic acetylcholine receptor M3 target
Mivacurium Cholinesterase target
Mivacurium Cholinesterase enzyme
Acetylcholine 溶质carrier family 22 member 5 transporter
Acetylcholine 溶质carrier family 22 member 1 transporter
Acetylcholine Muscarinic acetylcholine receptor M1 target
Acetylcholine Muscarinic acetylcholine receptor M2 target
Acetylcholine Muscarinic acetylcholine receptor M3 target
Acetylcholine Muscarinic acetylcholine receptor M4 target
Acetylcholine Neuronal acetylcholine receptor subunit alpha-7 target
Acetylcholine Acetylcholinesterase enzyme
Acetylcholine Cholinesterase enzyme