Moderate Menopausal Vasomotor Symptoms

Also known as:Moderate vasomotor symptoms

Drug Drug Name Drug Description
DB06401 Bazedoxifene A selective estrogen receptor modulator (SERM) used to treat moderate to severe vasomotor symptoms in menopause and osteoporosis alone or in combination with conjugated estrogens.
DB09381 Esterified estrogens A female hormone used to treat conditions related to estrogen deficiency and moderate to severe vasomotor menopausal symptoms in women.
DB13952 Estradiol acetate An estrogen used to treat vasomotor symptoms and moderate to severe vulvar and vaginal atrophy from menopause.
DB13954 Estradiol cypionate An estradiol prodrug used to treat vasomotor symptoms and hypoestrogenisms from hypogonadism.
DB13956 Estradiol valerate An estradiol prodrug used to treat some effects of menopause, hypoestrogenism, androgen dependant carcinoma of the prostate, and in combination products for endometriosis and contraception.
DB04574 Estrone sulfate An estrogen used as monotherapy or in several combination hormone replacement products for managing menopause symptoms and hormone disorders.
DB00367 Levonorgestrel A progestin found in oral and IUD contraceptives and at higher doses in emergency contraceptives.
DB00957 Norgestimate A progesterone used as a contraceptive and to treat acne vulgaris.
DB09317 Synthetic Conjugated Estrogens, A A mixture of estrogens used to treat a variety of postmenopausal symptoms, including vaginal atrophy and dyspareunia.
DB09318 Synthetic Conjugated Estrogens, B A mixture of estrogens used to treat a variety of postmenopausal symptoms, including vaginal dryness.
Drug Drug Name Target Type
DB06401 Bazedoxifene Estrogen receptor alpha target
DB06401 Bazedoxifene UDP-glucuronosyltransferase 1-4 enzyme
DB06401 Bazedoxifene Estrogen receptor beta target
DB06401 Bazedoxifene UDP-glucuronosyltransferase 1-8 enzyme
DB06401 Bazedoxifene UDP-glucuronosyltransferase 1-10 enzyme
DB09381 Esterified estrogens Cytochrome P450 3A4 enzyme
DB09381 Esterified estrogens Thyroxine-binding globulin carrier
DB13952 Estradiol acetate Estrogen receptor alpha target
DB13952 Estradiol acetate Nuclear receptor subfamily 1 group I member 2 target
DB13952 Estradiol acetate Sex hormone-binding globulin carrier
DB13952 Estradiol acetate Estrogen receptor beta target
DB13952 Estradiol acetate Cytochrome P450 1A2 enzyme
DB13952 Estradiol acetate UDP-glucuronosyltransferase 1-1 enzyme
DB13952 Estradiol acetate Serum albumin carrier
DB13952 Estradiol acetate Fatty acid-binding protein, intestinal carrier
DB13952 Estradiol acetate Cytochrome P450 3A4 enzyme
DB13952 Estradiol acetate Cytochrome P450 3A5 enzyme
DB13952 Estradiol acetate Cytochrome P450 3A7 enzyme
DB13952 Estradiol acetate Solute carrier family 22 member 2 transporter
DB13952 Estradiol acetate 溶质载体家庭22个成员1 transporter
DB13952 Estradiol acetate Solute carrier family 22 member 3 transporter
DB13952 Estradiol acetate Solute carrier organic anion transporter family member 2B1 transporter
DB13952 Estradiol acetate Solute carrier organic anion transporter family member 1A2 transporter
DB13952 Estradiol acetate Multidrug resistance-associated protein 7 transporter
DB13952 Estradiol acetate 溶质载体家庭22个成员11 transporter
DB13952 Estradiol acetate ATP-binding cassette sub-family G member 2 transporter
DB13952 Estradiol acetate Solute carrier organic anion transporter family member 1B1 transporter
DB13952 Estradiol acetate P-glycoprotein 1 transporter
DB13952 Estradiol acetate Cytochrome P450 1A1 enzyme
DB13952 Estradiol acetate Cytochrome P450 1B1 enzyme
DB13952 Estradiol acetate Cytochrome P450 2C19 enzyme
DB13952 Estradiol acetate Cytochrome P450 2C8 enzyme
DB13952 Estradiol acetate Cytochrome P450 2C9 enzyme
DB13952 Estradiol acetate Solute carrier family 22 member 8 transporter
DB13952 Estradiol acetate Solute carrier organic anion transporter family member 1B3 transporter
DB13952 Estradiol acetate Solute carrier organic anion transporter family member 1C1 transporter
DB13952 Estradiol acetate Solute carrier organic anion transporter family member 4A1 transporter
DB13952 Estradiol acetate Neuronal acetylcholine receptor subunit alpha-4 target
DB13952 Estradiol acetate Nuclear receptor coactivator 2 target
DB13952 Estradiol acetate G-protein coupled estrogen receptor 1 target
DB13952 Estradiol acetate ATP synthase subunit a target
DB13952 Estradiol acetate Beclin-1 target
DB13952 Estradiol acetate Estradiol 17-beta-dehydrogenase 2 target
DB13952 Estradiol acetate Estrogen-related receptor gamma target
DB13954 Estradiol cypionate Estrogen receptor alpha target
DB13954 Estradiol cypionate Nuclear receptor subfamily 1 group I member 2 target
DB13954 Estradiol cypionate Sex hormone-binding globulin carrier
DB13954 Estradiol cypionate Estrogen receptor beta target
DB13954 Estradiol cypionate Cytochrome P450 1A2 enzyme
DB13954 Estradiol cypionate UDP-glucuronosyltransferase 1-1 enzyme
DB13954 Estradiol cypionate Serum albumin carrier
DB13954 Estradiol cypionate Fatty acid-binding protein, intestinal carrier
DB13954 Estradiol cypionate Cytochrome P450 3A4 enzyme
DB13954 Estradiol cypionate Cytochrome P450 3A5 enzyme
DB13954 Estradiol cypionate Cytochrome P450 3A7 enzyme
DB13954 Estradiol cypionate Solute carrier family 22 member 2 transporter
DB13954 Estradiol cypionate 溶质载体家庭22个成员1 transporter
DB13954 Estradiol cypionate Solute carrier family 22 member 3 transporter
DB13954 Estradiol cypionate Solute carrier organic anion transporter family member 2B1 transporter
DB13954 Estradiol cypionate Solute carrier organic anion transporter family member 1A2 transporter
DB13954 Estradiol cypionate Multidrug resistance-associated protein 7 transporter
DB13954 Estradiol cypionate 溶质载体家庭22个成员11 transporter
DB13954 Estradiol cypionate ATP-binding cassette sub-family G member 2 transporter
DB13954 Estradiol cypionate Solute carrier organic anion transporter family member 1B1 transporter
DB13954 Estradiol cypionate P-glycoprotein 1 transporter
DB13954 Estradiol cypionate Cytochrome P450 1A1 enzyme
DB13954 Estradiol cypionate Cytochrome P450 1B1 enzyme
DB13954 Estradiol cypionate Cytochrome P450 2C19 enzyme
DB13954 Estradiol cypionate Cytochrome P450 2C8 enzyme
DB13954 Estradiol cypionate Cytochrome P450 2C9 enzyme
DB13954 Estradiol cypionate Solute carrier family 22 member 8 transporter
DB13954 Estradiol cypionate Solute carrier organic anion transporter family member 1B3 transporter
DB13954 Estradiol cypionate Solute carrier organic anion transporter family member 1C1 transporter
DB13954 Estradiol cypionate Solute carrier organic anion transporter family member 4A1 transporter
DB13954 Estradiol cypionate Neuronal acetylcholine receptor subunit alpha-4 target
DB13954 Estradiol cypionate Nuclear receptor coactivator 2 target
DB13954 Estradiol cypionate G-protein coupled estrogen receptor 1 target
DB13954 Estradiol cypionate ATP synthase subunit a target
DB13954 Estradiol cypionate Beclin-1 target
DB13954 Estradiol cypionate Estradiol 17-beta-dehydrogenase 2 target
DB13954 Estradiol cypionate Estrogen-related receptor gamma target
DB13956 Estradiol valerate Estrogen receptor alpha target
DB13956 Estradiol valerate Nuclear receptor subfamily 1 group I member 2 target
DB13956 Estradiol valerate Sex hormone-binding globulin carrier
DB13956 Estradiol valerate Estrogen receptor beta target
DB13956 Estradiol valerate Cytochrome P450 1A2 enzyme
DB13956 Estradiol valerate UDP-glucuronosyltransferase 1-1 enzyme
DB13956 Estradiol valerate Serum albumin carrier
DB13956 Estradiol valerate Fatty acid-binding protein, intestinal carrier
DB13956 Estradiol valerate Cytochrome P450 3A4 enzyme
DB13956 Estradiol valerate Cytochrome P450 3A5 enzyme
DB13956 Estradiol valerate Cytochrome P450 3A7 enzyme
DB13956 Estradiol valerate Solute carrier family 22 member 2 transporter
DB13956 Estradiol valerate 溶质载体家庭22个成员1 transporter
DB13956 Estradiol valerate Solute carrier family 22 member 3 transporter
DB13956 Estradiol valerate Solute carrier organic anion transporter family member 2B1 transporter
DB13956 Estradiol valerate Solute carrier organic anion transporter family member 1A2 transporter
DB13956 Estradiol valerate Multidrug resistance-associated protein 7 transporter
DB13956 Estradiol valerate 溶质载体家庭22个成员11 transporter
DB13956 Estradiol valerate ATP-binding cassette sub-family G member 2 transporter
DB13956 Estradiol valerate Solute carrier organic anion transporter family member 1B1 transporter
DB13956 Estradiol valerate P-glycoprotein 1 transporter
DB13956 Estradiol valerate Cytochrome P450 1A1 enzyme
DB13956 Estradiol valerate Cytochrome P450 1B1 enzyme
DB13956 Estradiol valerate Cytochrome P450 2C19 enzyme
DB13956 Estradiol valerate Cytochrome P450 2C8 enzyme
DB13956 Estradiol valerate Cytochrome P450 2C9 enzyme
DB13956 Estradiol valerate Solute carrier family 22 member 8 transporter
DB13956 Estradiol valerate Solute carrier organic anion transporter family member 1B3 transporter
DB13956 Estradiol valerate Solute carrier organic anion transporter family member 1C1 transporter
DB13956 Estradiol valerate Solute carrier organic anion transporter family member 4A1 transporter
DB13956 Estradiol valerate Neuronal acetylcholine receptor subunit alpha-4 target
DB13956 Estradiol valerate Nuclear receptor coactivator 2 target
DB13956 Estradiol valerate G-protein coupled estrogen receptor 1 target
DB13956 Estradiol valerate ATP synthase subunit a target
DB13956 Estradiol valerate Beclin-1 target
DB13956 Estradiol valerate Estradiol 17-beta-dehydrogenase 2 target
DB13956 Estradiol valerate Estrogen-related receptor gamma target
DB04574 Estrone sulfate Cytochrome P450 1A2 enzyme
DB04574 Estrone sulfate Cytochrome P450 3A4 enzyme
DB04574 Estrone sulfate Estrogen receptor alpha target
DB04574 Estrone sulfate Estrogen receptor beta target
DB04574 Estrone sulfate Sex hormone-binding globulin carrier
DB04574 Estrone sulfate Serum albumin carrier
DB04574 Estrone sulfate Cytochrome P450 2C9 enzyme
DB04574 Estrone sulfate Multidrug and toxin extrusion protein 1 transporter
DB04574 Estrone sulfate Multidrug and toxin extrusion protein 2 transporter
DB00367 Levonorgestrel Progesterone receptor target
DB00367 Levonorgestrel Estrogen receptor alpha target
DB00367 Levonorgestrel 3-oxo-5-alpha-steroid 4-dehydrogenase 1 target
DB00367 Levonorgestrel Cytochrome P450 3A4 enzyme
DB00367 Levonorgestrel Androgen receptor target
DB00367 Levonorgestrel Sex hormone-binding globulin target
DB00367 Levonorgestrel Glucocorticoid receptor target
DB00367 Levonorgestrel Cytochrome P450 3A5 enzyme
DB00957 Norgestimate Progesterone receptor target
DB00957 Norgestimate Estrogen receptor alpha target
DB00957 Norgestimate Canalicular multispecific organic anion transporter 1 transporter
DB00957 Norgestimate Cytochrome P450 3A4 enzyme
DB00957 Norgestimate Androgen receptor target
DB00957 Norgestimate Cytochrome P450 2B6 enzyme
DB00957 Norgestimate Cytochrome P450 2C9 enzyme
DB00957 Norgestimate UDP-glucuronosyltransferase 1-1 enzyme
DB00957 Norgestimate Serum albumin carrier
DB00957 Norgestimate Sex hormone-binding globulin carrier
DB00957 Norgestimate P-glycoprotein 1 transporter
DB09317 Synthetic Conjugated Estrogens, A Cytochrome P450 3A4 enzyme
DB09317 Synthetic Conjugated Estrogens, A Estrogen receptor alpha target
DB09317 Synthetic Conjugated Estrogens, A Thyroxine-binding globulin carrier
DB09318 Synthetic Conjugated Estrogens, B Estrogen receptor alpha target
DB09318 Synthetic Conjugated Estrogens, B Cytochrome P450 3A4 enzyme
DB09318 Synthetic Conjugated Estrogens, B Thyroxine-binding globulin carrier
Drug Drug Name Phase Status Count