This drug entry is astuband has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Propenidazole
- DrugBank Accession Number
- DB13319
- Background
-
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
-
Structure for Propenidazole (DB13319)
- Weight
-
Average: 267.241
Monoisotopic: 267.085520531 - Chemical Formula
- C11H13N3O5
- Synonyms
-
- Propenidazole
Pharmacology
- Indication
-
Not Available
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Avoid life-threatening adverse drug eventsImprove clinical decision support with information oncontraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events & improve clinical decision support. - Pharmacodynamics
-
Not Available
- Mechanism of action
- Not Available
- Absorption
-
Not Available
- Volume of distribution
-
Not Available
- Protein binding
-
Not Available
- Metabolism
- Not Available
- Route of elimination
-
Not Available
- Half-life
-
Not Available
- Clearance
-
Not Available
- Adverse Effects
-
Improve decision support & research outcomesWith structured adverse effects data, including:blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data. - Toxicity
-
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRsBrowse all" title="" id="snp-actions-info" class="drug-info-popup" href="javascript:void(0);">
- Not Available
Interactions
- Drug InteractionsLearn More" title="" id="structured-interactions-info" class="drug-info-popup" href="javascript:void(0);">
-
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your software阿曲库 The therapeutic efficacy of Atracurium can be increased when used in combination with Propenidazole. 阿曲库besylate The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Propenidazole. Botulinum toxin type A The therapeutic efficacy of Botulinum toxin type A can be increased when used in combination with Propenidazole. Cisatracurium The therapeutic efficacy of Cisatracurium can be increased when used in combination with Propenidazole. Decamethonium The therapeutic efficacy of Decamethonium can be increased when used in combination with Propenidazole. Doxacurium The therapeutic efficacy of Doxacurium can be increased when used in combination with Propenidazole. 加拉碘铵 The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Propenidazole. Letibotulinumtoxina The therapeutic efficacy of Letibotulinumtoxina can be increased when used in combination with Propenidazole. Metocurine The therapeutic efficacy of Metocurine can be increased when used in combination with Propenidazole. Metocurine iodide The therapeutic efficacy of Metocurine iodide can be increased when used in combination with Propenidazole. 
Identify potential medication risksEasily compare up to 40 drugs with our drug interaction checker.Get severity rating, description, and management advice.Learn more - Food Interactions
- Not Available
Categories
- ATC Codes
-
G01AF14 — Propenidazole
- G01AF — Imidazole derivatives
- G01A — ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
- G01 — GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
- G— GENITO URINARY SYSTEM AND SEX HORMONES
- Drug Categories
- Chemical TaxonomyProvided byClassyfire
-
- Description
- This compound belongs to the class of organic compounds known as nitroimidazoles. These are compounds containing an imidazole ring which bears a nitro group.
- Kingdom
- Organic compounds
- Super Class
- Organoheterocyclic compounds
- Class
- Azoles
- Sub Class
- Imidazoles
- Direct Parent
- Nitroimidazoles
- Alternative Parents
- 1,2,5-trisubstituted imidazoles/Imidazolyl carboxylic acids and derivatives/Nitroaromatic compounds/Beta-keto acids and derivatives/Fatty acid esters/Alpha-branched alpha,beta-unsaturated ketones/N-substituted imidazoles/Acryloyl compounds/Enoate esters/Enones show 11 more
- Substituents
- 1,2,5-trisubstituted-imidazole/Acryloyl-group/Allyl-type 1,3-dipolar organic compound/Alpha,beta-unsaturated carboxylic ester/Alpha,beta-unsaturated ketone/Alpha-branched alpha,beta-unsaturated-ketone/芳香的他teromonocyclic compound/Azacycle/Beta-keto acid/C-nitro compound show 28 more
- Molecular Framework
- 芳香的他teromonocyclic compounds
- External Descriptors
- Not Available
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- F0O89MB7QE
- CAS number
- 76448-31-2
- InChI Key
- GCHKUUOPYMFGEY-VMPITWQZSA-N
- InChI
-
InChI=1S/C11H13N3O5/c1-4-19-11(16)8(7(2)15)5-9-12-6-10(13(9)3)14(17)18/h5-6H,4H2,1-3H3/b8-5+
- IUPAC Name
-
ethyl (2E)-2-[(1-methyl-5-nitro-1H-imidazol-2-yl)methylidene]-3-oxobutanoate
- SMILES
-
CCOC(=O)C(=C\C1=NC=C(N1C)[N+]([O-])=O)\C(C)=O
References
- General References
- Not Available
- External Links
-
- ChemSpider
- 4950302
- ChEBI
- 135098
- ChEMBL
- CHEMBL1788390
- ZINC
- ZINC000000001990
- Wikipedia
- Propenidazole
Clinical Trials
- Clinical TrialsLearn More" title="" id="clinical-trials-info" class="drug-info-popup" href="javascript:void(0);">
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Phase Status Purpose Conditions Count
Pharmacoeconomics
- Manufacturers
-
Not Available
- Packagers
-
Not Available
- Dosage Forms
- Not Available
- Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
-
Property Value Source Water Solubility 0.344 mg/mL ALOGPS logP 1.11 ALOGPS logP 1.15 Chemaxon logS -2.9 ALOGPS pKa (Strongest Acidic) 18.17 Chemaxon pKa (Strongest Basic) 1.38 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 5 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 104.33 Å2 Chemaxon Rotatable Bond Count 6 Chemaxon Refractivity 65.03 m3·mol-1 Chemaxon Polarizability 25.72 Å3 Chemaxon Number of Rings 1 Chemaxon 生物利用度 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
-
Spectrum Spectrum Type Splash Key Predicted GC-MS Spectrum - GC-MS Predicted GC-MS Not Available Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS Not Available Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS Not Available
Drug created at June 23, 2017 20:39 / Updated at February 21, 2021 18:54