Acetic Acid Derivatives and Related Substances

Name
Acetic Acid Derivatives and Related Substances
Accession Number
DBCAT002310
Description

Not Available

ATC Classification
Drugs
Drug Drug Description
Sulindac An NSAID used to treat osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute subacromial bursitis or supraspinatus tendinitis, and acute gouty arthritis.
Etodolac An NSAID used to treat osteoarthritis and rheumatoid arthritis, as well as acute pain.
Zomepirac Zomepirac was indicated for the management of mild to severe pain.
Alclofenac Alclofenac is indicated in rheumatology, in particular for the treatment of rheumatoid arthritis, ankylosing spondylitis and, as an analgesic, in painful arthritic pathologies.
Bumadizone Bumadizone has been approved for use in Germany and Austria, it is a drug with anti-inflammatory, antipyretic, and analgesic properties, and was marketed for the treatment of both rheumatoid arthritis...
Oxametacin Not Annotated
Bufexamac An NSAID used to treat skin conditions like atopic eczema and inflammatory dermatoses.
Difenpiramide Not Annotated
Lonazolac Not Annotated
Proglumetacin A non-steroidal anti-inflammatory medication used to manage pain associated with various inflammatory conditions including rheumatoid arthritis and osteoarthritis.
Acemetacin A NSAID indicated in the treatment of pain and inflammation.
Indomethacin A nonsteroidal anti-inflammatory (NSAID) used for symptomatic management of chronic musculoskeletal pain conditions and to induce closure of a hemodynamically significant patent ductus arteriosus in premature infants.
Ketorolac An NSAID used to treat moderate to severe pain, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, menstrual disorders, and headaches.
Tolmetin An NSAID used to treat acute flares of various painful conditions and used for the long term management of osteoarthritis, rheumatoid arthritis, and juvenile arthritis.
Diclofenac An NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
Aceclofenac Aceclofenac表示疼痛的缓解d inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.
Fentiazac Not Annotated
Drugs & Drug Targets
Drug Target Type
Sulindac Prostaglandin G/H synthase 2 target
Sulindac Aldose reductase target
Sulindac Prostaglandin G/H synthase 1 target
Sulindac Mitogen-activated protein kinase 3 target
Sulindac Peroxisome proliferator-activated receptor delta target
Sulindac Prostaglandin D2 receptor 2 target
Sulindac Serum albumin carrier
Sulindac 溶质载体家庭22 member 6 transporter
Sulindac Cytochrome P450 1A1 enzyme
Sulindac Aldo-keto reductase family 1 member B10 target
Etodolac Prostaglandin G/H synthase 1 target
Etodolac Prostaglandin G/H synthase 2 target
Etodolac Cytochrome P450 2C9 enzyme
Etodolac UDP-glucuronosyltransferase 1-9 enzyme
Etodolac Retinoic acid receptor RXR-alpha target
Etodolac Serum albumin carrier
Etodolac 溶质载体家庭22 member 6 transporter
Etodolac UDP-glucuronosyltransferase 1-3 enzyme
Etodolac UDP-glucuronosyltransferase 1-10 enzyme
Etodolac UDP-glucuronosyltransferase 2B7 enzyme
Zomepirac Prostaglandin D2 receptor 2 target
Zomepirac Cytochrome P450 3A4 enzyme
Zomepirac Serum albumin carrier
Alclofenac Prostaglandin G/H synthase 2 target
Bufexamac Prostaglandin G/H synthase 1 target
Bufexamac Prostaglandin G/H synthase 2 target
Bufexamac Histone deacetylase 6 target
Bufexamac Histone deacetylase 10 target
Acemetacin Prostaglandin G/H synthase 1 target
Acemetacin Prostaglandin G/H synthase 2 target
Acemetacin UDP-glucuronosyltransferase 2B7 enzyme
Acemetacin Multidrug resistance-associated protein 1 transporter
Indomethacin Prostaglandin G/H synthase 1 target
Indomethacin Prostaglandin G/H synthase 2 target
Indomethacin Cytochrome P450 2C19 enzyme
Indomethacin UDP-glucuronosyltransferase 1-9 enzyme
Indomethacin Phospholipase A2, membrane associated target
Indomethacin Prostaglandin reductase 2 target
Indomethacin Lactoylglutathione lyase target
Indomethacin Prostaglandin D2 receptor 2 target
Indomethacin Peroxisome proliferator-activated receptor gamma target
Indomethacin Serum albumin carrier
Indomethacin Canalicular multispecific organic anion transporter 2 transporter
Indomethacin Multidrug resistance-associated protein 4 transporter
Indomethacin Multidrug resistance-associated protein 6 transporter
Indomethacin P-glycoprotein 1 transporter
Indomethacin Multidrug resistance-associated protein 1 transporter
Indomethacin Solute carrier organic anion transporter family member 1A2 transporter
Indomethacin 溶质载体家庭22 member 6 transporter
Indomethacin 溶质载体家庭22 member 8 transporter
Indomethacin Canalicular multispecific organic anion transporter 1 transporter
Indomethacin ATP-binding cassette sub-family C member 11 transporter
Indomethacin 溶质载体家庭22 member 11 transporter
Indomethacin Sodium/bile acid cotransporter transporter
Indomethacin 溶质载体家庭22 member 7 transporter
Indomethacin Cytochrome P450 2C9 enzyme
Indomethacin UDP-glucuronosyltransferase 1-1 enzyme
Indomethacin Liver carboxylesterase 1 enzyme
Indomethacin UDP-glucuronosyltransferase 2B7 enzyme
Indomethacin Peroxisome proliferator-activated receptor alpha target
Indomethacin Aldo-keto reductase family 1 member C3 target
Indomethacin Solute carrier organic anion transporter family member 1B1 transporter
Indomethacin Bile salt export pump transporter
Indomethacin Interferon-induced, double-stranded RNA-activated protein kinase target
Indomethacin Human Cyclooxygenases target
Ketorolac Prostaglandin G/H synthase 1 target
Ketorolac Prostaglandin G/H synthase 2 target
Ketorolac UDP-glucuronosyltransferase 2B7 enzyme
Ketorolac Cytochrome P450 2C8 enzyme
Ketorolac Cytochrome P450 2C9 enzyme
Tolmetin Prostaglandin G/H synthase 1 target
Tolmetin Prostaglandin G/H synthase 2 target
Tolmetin 溶质载体家庭22 member 6 transporter
Tolmetin Tryptophan 2,3-dioxygenase enzyme
Tolmetin Myeloperoxidase enzyme
Tolmetin Serum albumin carrier
Diclofenac Prostaglandin G/H synthase 1 target
Diclofenac Prostaglandin G/H synthase 2 target
Diclofenac Transthyretin carrier
Diclofenac Cytochrome P450 2C9 enzyme
Diclofenac Cytochrome P450 2C19 enzyme
Diclofenac Cytochrome P450 1A2 enzyme
Diclofenac Cytochrome P450 2C8 enzyme
Diclofenac Serum albumin carrier
Diclofenac Multidrug resistance-associated protein 4 transporter
Diclofenac Multidrug resistance-associated protein 1 transporter
Diclofenac 溶质载体家庭22 member 6 transporter
Diclofenac 溶质载体家庭22 member 8 transporter
Diclofenac Solute carrier organic anion transporter family member 1C1 transporter
Diclofenac 溶质载体家庭22 member 11 transporter
Diclofenac UDP-glucuronosyltransferase 2B7 enzyme
Diclofenac Cytochrome P450 3A4 enzyme
Diclofenac Cytochrome P450 2B6 enzyme
Diclofenac Cytochrome P450 2C18 enzyme
Diclofenac Cytochrome P450 2E1 enzyme
Diclofenac Solute carrier organic anion transporter family member 1B1 transporter
Diclofenac Bile salt export pump transporter
Diclofenac UDP-glucuronosyltransferase 1-3 enzyme
Diclofenac UDP-glucuronosyltransferase 1-9 enzyme
Diclofenac UDP-glucuronosyltransferase 2B4 enzyme
Diclofenac Arachidonate 5-lipoxygenase enzyme
Diclofenac Sodium channel protein type 4 subunit alpha transporter
Diclofenac Acid-sensing ion channel 1 transporter
Diclofenac Potassium voltage-gated channel subfamily KQT member 2 transporter
Diclofenac Potassium voltage-gated channel subfamily KQT member 3 transporter
Diclofenac Phospholipase A2, membrane associated enzyme
Diclofenac P-glycoprotein 1 transporter
Aceclofenac Cytochrome P450 2C9 enzyme
Aceclofenac Prostaglandin G/H synthase 2 target
Aceclofenac Prostaglandin G/H synthase 1 target