Angiotensin II receptor blockers (ARBs) and calcium channel blockers

All categories
Name
Angiotensin II receptor blockers (ARBs) and calcium channel blockers
Accession Number
DBCAT004595
Description

Not Available

ATC Classification
Drugs
Drug Drug Description
Valsartan An angiotensin-receptor blocker used to manage hypertension alone or in combination with other antihypertensive agents and to manage heart failure in patients who are intolerant to ACE inhibitors.
Olmesartan An angiotensin receptor blocker (ARB) used in the treatment of hypertension.
Amlodipine A calcium channel blocker used to treat hypertension and angina.
Lercanidipine A calcium channel blocker for the management of hypertension.
Losartan An angiotensin receptor blocker used to treat hypertension and diabetic nephropathy, and is used to reduce the risk of stroke.
Telmisartan An ARB used to treat hypertension, diabetic nephropathy, and congestive heart failure.
Irbesartan An angiotensin receptor blocker used to treat hypertension, delay progression of diabetic nephropathy, and treat congestive heart failure.
Candesartan An angiotensin-receptor blocker indicated in the treatment of hypertension.
Fimasartan An angiotensin II receptor antagonist (ARB) used to treat hypertension and heart failure.
Drugs & Drug Targets
Drug Target Type
Valsartan Type-1 angiotensin II receptor target
Valsartan Cytochrome P450 2C9 enzyme
Valsartan Solute carrier organic anion transporter family member 1B3 transporter
Valsartan Solute carrier organic anion transporter family member 1B1 transporter
Valsartan Canalicular multispecific organic anion transporter 1 transporter
Olmesartan Type-1 angiotensin II receptor target
Olmesartan Canalicular multispecific organic anion transporter 1 transporter
Olmesartan Solute carrier organic anion transporter family member 1B3 transporter
Olmesartan Solute carrier organic anion transporter family member 1B1 transporter
Olmesartan Bile salt export pump transporter
Amlodipine Carbonic anhydrase 1 target
Amlodipine Cytochrome P450 3A4 enzyme
Amlodipine Voltage-dependent L-type calcium channel subunit alpha-1C target
Amlodipine Cytochrome P450 1A1 enzyme
Amlodipine Cytochrome P450 2B6 enzyme
Amlodipine Voltage-dependent N-type calcium channel subunit alpha-1B target
Amlodipine Voltage-dependent L-type calcium channel subunit beta-1 target
Amlodipine Voltage-dependent calcium channel subunit alpha-2/delta-3 target
Amlodipine Cytochrome P450 3A5 enzyme
Amlodipine P-glycoprotein 1 transporter
Amlodipine Cytochrome P450 2C8 enzyme
Amlodipine Cytochrome P450 2D6 enzyme
Amlodipine Sphingomyelin phosphodiesterase target
Amlodipine Voltage-dependent T-type calcium channel subunit alpha-1I target
Amlodipine Voltage-dependent N-type calcium channel target
Lercanidipine Voltage-dependent calcium channel gamma-1 subunit target
Lercanidipine Cytochrome P450 3A4 enzyme
Lercanidipine Cytochrome P450 3A5 enzyme
Lercanidipine Cytochrome P450 3A7 enzyme
Lercanidipine Cytochrome P450 2D6 enzyme
Losartan Type-1 angiotensin II receptor target
Losartan Cytochrome P450 3A4 enzyme
Losartan Cytochrome P450 2C9 enzyme
Losartan P-glycoprotein 1 transporter
Losartan Solute carrier family 22 member 6 transporter
Losartan UDP-glucuronosyltransferase 1-1 enzyme
Losartan UDP-glucuronosyltransferase 1-3 enzyme
Losartan UDP-glucuronosyltransferase 1-10 enzyme
Losartan UDP-glucuronosyltransferase 2B7 enzyme
Losartan UDP-glucuronosyltransferase 2B17 enzyme
Losartan Cytochrome P450 2C19 enzyme
Losartan Serum albumin carrier
Losartan Solute carrier family 22 member 12 transporter
Losartan Solute carrier family 2, facilitated glucose transporter member 9 transporter
Losartan Bile salt export pump transporter
Losartan Cytochrome P450 2C8 enzyme
Telmisartan Type-1 angiotensin II receptor target
Telmisartan Peroxisome proliferator-activated receptor gamma target
Telmisartan P-glycoprotein 1 transporter
Telmisartan Canalicular multispecific organic anion transporter 1 transporter
Telmisartan ATP-binding cassette sub-family G member 2 transporter
Telmisartan Cytochrome P450 2C19 enzyme
Telmisartan Bile salt export pump transporter
Telmisartan UDP-glucuronosyltransferase 1-3 enzyme
Irbesartan Type-1 angiotensin II receptor target
Irbesartan Transcription factor AP-1 target
Irbesartan Cytochrome P450 2C9 enzyme
Irbesartan Cytochrome P450 2C8 enzyme
Irbesartan UDP-glucuronosyltransferase 1-3 enzyme
Irbesartan Prostaglandin G/H synthase 1 enzyme
Irbesartan Cytochrome P450 3A4 enzyme
Irbesartan Serum albumin carrier
Irbesartan alpha1-acid glycoprotein carrier
Candesartan Type-1 angiotensin II receptor target
Candesartan Cytochrome P450 2C8 enzyme
Candesartan Cytochrome P450 2C9 enzyme
Candesartan P-glycoprotein 1 transporter
Candesartan UDP-glucuronosyltransferase 1-3 enzyme
Candesartan Prostaglandin G/H synthase 1 enzyme
Candesartan Solute carrier organic anion transporter family member 1B1 transporter
Fimasartan Type-1 angiotensin II receptor target
Fimasartan Solute carrier organic anion transporter family member 1B1 transporter
Fimasartan ATP-binding cassette sub-family G member 2 transporter