Antipropulsives

Name
Antipropulsives
Accession Number
DBCAT002293
Description

Not Available

ATC Classification
Drugs
Drug Drug Description
Loperamide A long acting antidiarrheal used to control nonspecific diarrhea and chronic diarrhea caused by inflammatory bowel disease, or gastroenteritis.
Diphenoxylate An antidiarrheal medication used with atropine to manage diarrhea.
Difenoxin An antidiarrheal agent used as an adjunct for the management of acute nonspecific diarrhea and acute exacerbations of chronic functional diarrhea.
Opium A medication used to treat moderate to severe pain.
Loperamide oxide Not Annotated
Eluxadoline A mixed mu-opioid receptor agonist used to treat irritable bowel syndrome with diarrhea.
Drugs & Drug Targets
Drug Target Type
Loperamide Voltage-dependent P/Q-type calcium channel subunit alpha-1A target
Loperamide Mu-type opioid receptor target
Loperamide Calmodulin target
Loperamide Pro-opiomelanocortin target
Loperamide Delta-type opioid receptor target
Loperamide Cytochrome P450 3A4 enzyme
Loperamide P-glycoprotein 1 transporter
Loperamide Kappa-type opioid receptor target
Loperamide Cytochrome P450 2C8 enzyme
Loperamide Cytochrome P450 2B6 enzyme
Loperamide Cytochrome P450 2D6 enzyme
Loperamide Potassium voltage-gated channel subfamily H member 2 target
Diphenoxylate Mu-type opioid receptor target
Diphenoxylate Delta-type opioid receptor target
Opium Delta-type opioid receptor target
Opium Kappa-type opioid receptor target
Opium Mu-type opioid receptor target
Opium Serum albumin carrier
Opium Beta-2-microglobulin carrier
Opium Cytochrome P450 2D6 enzyme
Opium Cytochrome P450 3A4 enzyme
Eluxadoline Mu-type opioid receptor target
Eluxadoline Delta-type opioid receptor target
Eluxadoline Kappa-type opioid receptor target
Eluxadoline Solute carrier organic anion transporter family member 1B1 transporter
Eluxadoline Canalicular multispecific organic anion transporter 1 transporter
Eluxadoline Solute carrier family 22 member 8 transporter