Carbenicillin disodiumProduct ingredient forCarbenicillin
- Name
- Carbenicillin disodium
- Drug Entry
-
Carbenicillin
Broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function.
- Accession Number
- DBSALT001334
- Structure
-
Structure for Carbenicillin disodium (DBSALT001334)
- Synonyms
- Not Available
- UNII
- 9TS4B3H261
- CAS Number
- 4800-94-6
- Weight
-
Average: 422.36
Monoisotopic: 422.05244598 - Chemical Formula
- C17H16N2Na2O6S
- InChI Key
- RTYJTGSCYUUYAL-YCAHSCEMSA-L
- InChI
-
InChI=1S/C17H18N2O6S.2Na/c1-17(2)11(16(24)25)19-13(21)10(14(19)26-17)18-12(20)9(15(22)23)8-6-4-3-5-7-8;;/h3-7,9-11,14H,1-2H3,(H,18,20)(H,22,23)(H,24,25);;/q;2*+1/p-2/t9?,10-,11+,14-;;/m1../s1
- IUPAC Name
-
disodium (2S,5R,6R)-6-(2-carboxylato-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
- SMILES
-
[Na+].[Na+].[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)C(C([O-])=O)C1=CC=CC=C1)C([O-])=O
- External Links
-
- KEGG Compound
- C13967
- ChemSpider
- 19694
- ChEBI
- 34609
- ChEMBL
- CHEMBL606260
- Wikipedia
- Carbenicillin
- Predicted Properties
-
Property Value Source Water Solubility 0.4 mg/mL ALOGPS logP 1.71 ALOGPS logP 0.82 Chemaxon logS -3 ALOGPS pKa (Strongest Acidic) 3.11 Chemaxon pKa (Strongest Basic) -6.3 Chemaxon Physiological Charge -2 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 129.67 Å2 Chemaxon Rotatable Bond Count 5 Chemaxon Refractivity 112.49 m3·mol-1 Chemaxon Polarizability 35.15 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon 医学博士DR-like Rule No Chemaxon
