Mrv1572003271614432D 37 41 0 0 0 0 999 V2000型-3.2176 1.9800 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.2176 1.1550 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.9189 0.7425 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.6614 1.1550 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -4.6614 1.9800 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.9189 2.3926 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 -2.5163 2.3926 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.7738 1.9800 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.7738 1.1550 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.5163 0.7425 0.0000 C0 0 0 0 0 0 0 0 0 0 0 0 -1.0725 2.3926 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.3712 1.9800 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.0725 0.7425 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 -0.3712 1.1550 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.9189 -0.0824 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 -3.1763 -0.4950 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -3.1763 -1.3201 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4750 -1.7326 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.7738 -1.3201 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.7738 -0.4537 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -2.4750 -0.0412 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -1.0313 -1.6913 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 -0.3300 -1.2788 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.4125 -1.6913 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 -0.3300 -0.4537 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 1.1138 -1.2375 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.8151 -1.6500 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 1.1138 -0.4125 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 2.5163 -1.2375 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2589 -1.6500 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9189 -1.1963 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.9189 -0.3713 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.2176 0.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.5163 -0.4125 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.6615 0.0000 0.0000 F 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 -2.3926 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.8250 -2.3926 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 2 3 1 0 0 0 0 3 4 2 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 1 6 1 0 0 0 0 1 7 1 0 0 0 0 7 8 2 0 0 0 0 8 9 1 0 0 0 0 9 10 2 0 0 0 0 2 10 1 0 0 0 0 8 11 1 0 0 0 0 11 12 1 0 0 0 0 9 13 1 0 0 0 0 13 14 1 0 0 0 0 3 15 1 0 0 0 0 15 16 1 0 0 0 0 16 17 2 0 0 0 0 17 18 1 0 0 0 0 18 19 2 0 0 0 0 19 20 1 0 0 0 0 20 21 2 0 0 0 0 16 21 1 0 0 0 0 19 22 1 0 0 0 0 22 23 1 0 0 0 0 23 24 1 0 0 0 0 23 25 2 0 0 0 0 24 26 1 0 0 0 0 26 27 1 0 0 0 0 26 28 2 0 0 0 0 27 29 1 0 0 0 0 29 30 2 0 0 0 0 30 31 1 0 0 0 0 31 32 2 0 0 0 0 32 33 1 0 0 0 0 33 34 2 0 0 0 0 29 34 1 0 0 0 0 32 35 1 0 0 0 0 36 37 1 0 0 0 0 37 24 1 0 0 0 0 24 36 1 0 0 0 0 M END >
DB08875 >
drugbank >
COC1 = CC2 = C (C = C1OC) C (OC1 = CC = C (NC (= O) C3 (CC3) C (= O) NC3 = CC = C (F) C = C3) C = C1) = CC = N2 >
第16 - 25 InChI = 1 s / C28H24FN3O5 / c1-35-24-15-21-22 ((24) 36-2) 30-14-11-23 (21) 30-14-11-23 (8-10-20) 32-27 (34) 28 (12-13-28) 26 (33) 31-18-5-3-17 (29) 31-18-5-3-17 / h3-11 14-16H, 12-13H2, 1-2H3, (H, 31岁,33)(H, 32岁,34)>
ONIQOQHATWINJY-UHFFFAOYSA-N >
C28H24FN3O5 >
501.514 >
501.169999048 >
5 >
61年>
51.49370830255501 >
1 >
2 >
0 >
0 >
N ' 1 - {4 - [(6 7-dimethoxyquinolin-4-yl)氧]苯基}n1 - (4-fluorophenyl) cyclopropane-1 1-dicarboxamide >
4.01 >
4.658062448 >
-5.40 >
1 >
5 >
0 >
14.47114923183193 >
13.46188656926935 >
5.895706033147246 >
98.78 >
136.1206 >
8 >
0 >
1.99 -03 g/l >
cabozantinib >
0 >
DB08875 >
DB05153 >
批准;临床实验的>
Cabozantinib >
Cabozantinib >
Cabometyx;Cometriq >
苹果酸卡博赞替尼$$$$