Histamine dihydrochlorideProduct ingredient forHistamine
- Name
- Histamine dihydrochloride
- Drug Entry
-
Histamine
A depressor amine derived by enzymatic decarboxylation of histidine. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.
- Accession Number
- DBSALT002193
- Structure
-
Structure for Histamine dihydrochloride (DBSALT002193)
- Synonyms
- 1H-imidazole-4-ethanamine dihydrochloride/1H-imidazole-5-ethanamine, hydrochloride (1:2)/2-(4-imidazolyl)ethylamine dihydrochloride/HD-O/Histaminum hydrochloricum
- External IDs
- NSC-257873
- UNII
- 3POA0Q644U
- CAS Number
- 56-92-8
- Weight
-
Average: 184.067
单一同位素的:183.033002781 - Chemical Formula
- C5H11Cl2N3
- InChI Key
- PPZMYIBUHIPZOS-UHFFFAOYSA-N
- InChI
-
InChI=1S/C5H9N3.2ClH/c6-2-1-5-3-7-4-8-5;;/h3-4H,1-2,6H2,(H,7,8);2*1H
- IUPAC Name
-
2-(1H-imidazol-5-yl)ethan-1-amine dihydrochloride
- SMILES
-
Cl.Cl.NCCC1=CN=CN1
- External Links
-
- ChemSpider
- 5613
- ChEMBL
- CHEMBL1533310
- Wikipedia
- Histamine_dihydrochloride
- Predicted Properties
-
Property Value Source Water Solubility 165.0 mg/mL ALOGPS logP -0.88 ALOGPS logP -1 Chemaxon logS 0.17 ALOGPS pKa (Strongest Acidic) 13.5 Chemaxon pKa (Strongest Basic) 9.79 Chemaxon Physiological Charge 2 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 54.7 Å2 Chemaxon Rotatable Bond Count 2 Chemaxon Refractivity 32.23 m3·mol-1 Chemaxon Polarizability 11.98 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon
