Adrenergic alpha-2 Receptor Antagonists

Name
Adrenergic alpha-2 Receptor Antagonists
Accession Number
DBCAT001356
Description

Drugs that bind to and block the activation of ADRENERGIC ALPHA-2 RECEPTORS.

Drugs
Drug Drug Description
Atipamezole For the reversal of the sedative and analgesic effects of dexmedetomidine and medetomidine in dogs.
ORM-12741 ORM-12741 has been used in trials studying the basic science and treatment of Alzheimer's Disease.
Idazoxan Idazoxan has been used in trials studying the basic science of Molecular Imaging, Alzheimer Disease, and Major Depressive Disorder.
Yohimbine An alpha-2-adrenergic blocker and sympatholytic found in supplements used to.
Lurasidone An atypical antipsychotic used to treat schizophrenia and depressive episodes associated with bipolar I disorder.
Mirtazapine A tetracyclic antidepressant used in the treatment of major depression and is used off-label as a drug for insomnia and to increase appetite.
Esmirtazapine Investigated for use/treatment in insomnia and sleep disorders.
Drugs & Drug Targets
Drug Target Type
Yohimbine Alpha-2A adrenergic receptor target
Yohimbine Alpha-2B adrenergic receptor target
Yohimbine Alpha-2C adrenergic receptor target
Yohimbine 5-hydroxytryptamine receptor 1A target
Yohimbine 5-hydroxytryptamine receptor 1B target
Yohimbine 5-hydroxytryptamine receptor 1D target
Yohimbine Dopamine D2 receptor target
Yohimbine Dopamine D3 receptor target
Yohimbine 5-hydroxytryptamine receptor 2A target
Yohimbine 5-hydroxytryptamine receptor 2C target
Yohimbine Cytochrome P450 2D6 enzyme
Yohimbine Cytochrome P450 3A4 enzyme
Yohimbine ATP-sensitive potassium channel target
Yohimbine 5-hydroxytryptamine receptor 2B target
Lurasidone Cytochrome P450 3A4 enzyme
Lurasidone Dopamine D2 receptor target
Lurasidone 5-hydroxytryptamine receptor 2A target
Lurasidone 5-hydroxytryptamine receptor 7 target
Lurasidone 5-hydroxytryptamine receptor 1A target
Lurasidone Alpha-2C adrenergic receptor target
Lurasidone Alpha-2A adrenergic receptor target
Mirtazapine 5-hydroxytryptamine receptor 2A target
Mirtazapine 5HT3 serotonin receptor target
Mirtazapine Alpha-2A adrenergic receptor target
Mirtazapine 5-hydroxytryptamine receptor 2C target
Mirtazapine Kappa-type opioid receptor target
Mirtazapine Histamine H1 receptor target
Mirtazapine Cytochrome P450 1A2 enzyme
Mirtazapine Cytochrome P450 3A4 enzyme
Mirtazapine Cytochrome P450 2D6 enzyme
Mirtazapine Alpha-1 adrenergic receptors target
Mirtazapine Sodium-dependent serotonin transporter transporter
Esmirtazapine Cytochrome P450 2D6 enzyme
Esmirtazapine Histamine H1 receptor target
Esmirtazapine 5-hydroxytryptamine receptor 2 target
Esmirtazapine Alpha-2 adrenergic receptors target