Phosphinic Acids

Name
Phosphinic Acids
Accession Number
DBCAT000924
Description

Inorganic or organic derivatives of phosphinic acid, H2PO(OH). They include phosphinates and phosphinic acid esters.

Drugs
Drug Drug Description
Fosinopril An ACE inhibitor used to treat mild to moderate hypertension, congestive heart failure, and to slow the progression of renal disease in hypertensive diabetics.
Fosinoprilat Fosinoprilat is the active phosphinic acid metabolite of prodrug fosinopril, which is activated by esterases in vivo. It binds zinc with phosphinic acid group.
Drugs & Drug Targets
Drug Target Type
Fosinopril Angiotensin-converting enzyme target
Fosinopril Solute carrier family 15 member 1 transporter
Fosinopril Solute carrier family 15 member 2 transporter